Fellowship Scholarly Activity: Past & Present
Our fellows engage in (and have engaged in) in novel and innovative research projects.
Fellowship Scholarly Activity: Past & Present
Our fellows engage in (and have engaged in) in novel and innovative research projects.
Current Fellows' Research Projects
Research projects for first-year fellows are determined and developed at the start of the academic year. This year's PGY-4 fellows' research projects will be announced at a later date. Check back for more information as it becomes available.
Second-Year Fellows |
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The effect of COVID-19 on maternal mental health and the provisions of human milk at discharge for preterm infants |
Effect of Post-Death Family Meeting on Parental Bereavement |
IAIP-HMGB1 Interaction in LPS-Induced Preterm Sheep Brain Injury Quality Improvement Research Project: Delayed Cord Clamping in the PTI |
Quality Improvement Research Projects:
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Past Fellows' Research Projects
Project Title |
Resultant Publication, etc |
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Association between Dietary Intake and Severe BPD in ELBW infants |
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Quality Improvement Initiative to Improve Admission Temperatures to the NICU |
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Endotracheal Aspirate vs. Distal Protected Catheter in Neonates with VAP and the Impact on Antibiotic Usage |
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Intrapartum Fever/Clinical Chorioamnionitis |
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Association between Neighborhood Risk and the Neurodevelopmental Outcomes of Extreme to Moderate Preterm Infants |
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Project Title |
Resultant Publication, etc. |
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The role of biglycan and decorin in PPROM |
Mennella JM, Underhill LA, Collis S, Lambert-Messerlian GM, Tucker R, Lechner BE. Serum Decorin, Biglycan, and Extracellular Matrix Component Expression in Preterm Birth. Reprod Sci. 2021 Jan;28(1):228-236. doi: 10.1007/s43032-020-00251-1. Epub 202link to Reprod Sci article0 Aug 17. PMID: 32804350; PMCID: PMC7782456. |
The role of Chitinase 3-like 1 (Chi3L1) in chorioamnionitis and preterm labor |
Najrana T, Mahadeo A, Abu-Eid R, Kreienberg E, Schulte V, Uzun A, Schorl C, Goldberg L, Quesenberry P, Sanchez-Esteban J. Mechanical stretch regulates the expression of specific miRNA in extracellular vesicles released from lung epithelial cells. J Cell Physiol. 2020 Nov;235(11):8210-8223. doi: 10.1002/jcp.29476. Epub 2020 Jan 22. PMID: 31970782; PMCID: PMC7374064. |
Bridging Connections: A language intervention study of preterm infants in the NICU |
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Project |
Resultant Publication, etc. |
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Prenatal exposure to perfluoroalkyl substances (PFAS), infant birthweight, and adipocytokines: The HOME Study |
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Prenatal exposure to stressful life events and infant breastfeeding: Pregnancy Risk Assessment Monitoring Study |
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Neonatal adipocytokines + growth during childhood |
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Co-leader/Clinical Director: Design + Health |
D'Cruz R |
Course Director: Biomedical Engineering (Brown) Capstone: |
D'Cruz R patent application for transilluminator device developed as a result of the course |
CPAP vs unsynchronized NIPPV at equal MAP |
Gupta A |
Survey of ventilation practices in the USA and Canada |
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Use of whole exome sequencing to diagnose a rare case of congenital diarrhea in a newborn |
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Bench evaluation of NICU and non-NICU ventilators using an active lung model (ASL 5000) |
Gupta A |
2018 Project | Resultant Publication, etc. |
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Ambient noise production by high-frequency neonatal ventilators | Goldstein J, Laliberte A, Keszler M. Ambient Noise Production by High-Frequency Neonatal Ventilators. J Pediatr. 2019 Jan;204:157-161. doi: 10.1016/j.jpeds.2018.08.029. Epub 2018 Sep 26. PMID: 30268396. |
Hepatic gene expression during the perinatal transition in the rat | Hurley E, Zabala V, Boylan JM, Gruppuso PA, Sanders JA. Hepatic Gene Expression During the Perinatal Transition in the Rat. Gene Expr. 2018 Dec 14;19(1):1-13. doi: 10.3727/105221618X15293258688953. Epub 2018 Jun 21. PMID: 29929573; PMCID: PMC6290323. |
Evidence of lysosomal biogenesis proteome defect and impaired autophagy in preeclampsia |
2017 Project | Resultant Publication, etc. |
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Placental findings in newborns with hypoxic-ischemic encephalopathy (HIE) compared to newborns admitted to a NICU | Bingham A, Gundogan F, Rand K, Laptook AR. Placental findings among newborns with hypoxic ischemic encephalopathy. J Perinatol. 2019 Apr;39(4):563-570. doi: 10.1038/s41372-019-0334-9. Epub 2019 Feb 15. PMID: 30770878. |
Dietary supplementation with medium-chain triglycerides reduces Candida GI colonization in preterm infants | Arsenault AB, Gunsalus KTW, Laforce-Nesbitt SS, Przystac L, DeAngelis EJ, Hurley ME, Vorel ES, Tucker R, Matthan NR, Lichtenstein AH, Kumamoto CA, Bliss JM. Dietary Supplementation With Medium-Chain Triglycerides Reduces Candida Gastrointestinal Colonization in Preterm Infants. Pediatr Infect Dis J. 2019 Feb;38(2):164-168. doi: 10.1097/INF.0000000000002042. PMID: 29596218; PMCID: PMC6604858. |
Characterization of preterm umbilical cord-derived mesenchymal stromal cells for use in reversal of neonatal lung injury | Â |
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Innovation in Action!
Ravi D'Cruz, MD, pictured above with students in the Biomedical Engineering program back in 2018, used his background in design (former architect) to engage students in innovative biomedical projects, including development of a transilluminator. Dr. D'Cruz is emblematic of our fellows who reach outside the box to find a research niche that works for them.Â
SPOTLIGHT: Ravi D'Cruz, MD; 2019 Fellowship Graduate
Biomedical innovation: Dr. Ravi D'Cruz, a 2019 fellow in neonatal and perinatal medicine at Women and Infants Hospital, worked with Brown biomedical engineering students to design a new device to help doctors perform blood draws and other procedures in the neonatal intensive care unit.